Have you read up on boundaries and setting limits? Are you two in counseling?
I have learned and applied quite a bit about setting boundaries, including the ones from this site
https://www.bpdfamily.com/content/setting-boundaries We see individual therapists. We tried couples counseling a few years ago, but she would either go on a dysregulated blaming tirade or completely shut down.
Tonight my wife brought up in conversation that she plans only to go for the 5 days. I can still call to check up on them. I take her at her word on this for now.
Have you noticed any other red flags of her being unfaithful?
There seems to be a lot of text messages/notifications coming in at odd times of the night. She gets very defensive when I ask where she is going, even if it is a simple trip to the store. These may be coincidental and not indicative of an affair. She has seemed emotionally distant lately, but she goes through cycles of this based on her diagnosis.