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Author Topic: FAQ: Are amino acids and probiotics helpful to pwBPD?  (Read 380 times)
lasagna
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« on: May 31, 2007, 01:40:10 PM »

Omega 3 fish oil evens out moods.

This is medically substantiated. Psychiatrists prescribe it, usually as an addition to SSRI.

The added benefit is that the fish oil is anti-inflammatory (for those of us who are aging) and good for the heart. It is sold in odorless, tasteless pills. No fishy burps. Make sure you buy a good brand that assures no mercury. This is one item that I overlook price for quality control.
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Healthy88
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« Reply #1 on: January 11, 2017, 08:42:25 PM »

Recent studies seem to be confirming fish oils are effective, but can take 3-4 months to see results... .similar to antidepressants so they have to stick with it. Just ordered low dose Ashwaganda (Indian ginseng) to try with the fish oils. From all my research so far, they seem like 2 natural supplements to try to help with BPD.
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Tattered Heart
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« Reply #2 on: January 12, 2017, 08:40:53 AM »

My uBPDh takes L-Thienine (L-γ-glutamylethylamide and N⁵-ethyl-L-glutamine) and I can see it work within minutes of him taking it. He has also taken 5HTP. healthy and I were talking about this just a couple days ago. There are a few amino acids out there to help with behavior. I think he has tried Ashwaganda (Indian ginseng) too. A daily probiotic works wonders with him too. He has also taken tumeric (Curcuma longa) and I have never seen him so mellow before, but tumeric cannot be taken on a long term basis.

For my H, diet makes a huge difference. If he eats gluten, deep fried food (especially McDonald's chicken nuggets), or too much sugar he tends to dysregulate. We try to limit gluten and eat paleo/Whole 30 as much as possible. When we steadily eat this, his mood changes immensely.

A couple years ago we both tried a GAPS diet. It stands for Gut & Psychology Syndrome diet. THe premise of the diet is to eliminate anything that can cause leaky gut and to begin healing your gut. Our mental wellness and immune system both start in our digestive system. It's a pretty intensive diet that basically cuts almost everything out and you add in foods every few days to see if you have a reaction to it. This diet helps people with autism, auto immune disorders, excessive inflammation, and behavioral issues. It's a very difficult diet to maintain so that's why we began doing paleo instead.
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Hope deferred makes the heart sick, but a longing fulfilled is a tree of life Proverbs 13:12

Kyanite

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« Reply #3 on: January 12, 2017, 09:48:22 AM »

An unequivocal yes.

DH used to have real anger management issues, to the point that he was starting to grab and intimidate the kids when they were little. Right around that time we discovered that he had celiac. We removed gluten (and some other food allergies) from his diet, and he calmed down significantly. He describerd it as having "space" to consider the action before responding. He still gets angry and throws things occasionally or swears at traffic, but the level and fequency is SO much less. If he eats an allergic food, his mood is the first thing to go.

As for supplements, we have found the most success with a hefty probiotic - one with at least 30 different strains. Other supps are hard to tell, as he is not consistent with taking them except the probiotics.
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Healthy88
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« Reply #4 on: January 24, 2017, 10:55:14 PM »

Hi All,

I want to correct a comment about probiotics and Kefir. Apparently, there are some oral probiotics that contain more live cultures than Kefir, even though Kefir has a lot and is a great source of probiotics. I personally, noticed some benefits from Kefir that I did not with oral probiotics. I just wanted to correct a previous incorrect comment FYI!
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Kyanite

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« Reply #5 on: January 26, 2017, 10:09:27 AM »

Hi All,

I want to correct a comment about probiotics and Kefir. Apparently, there are some oral probiotics that contain more live cultures than Kefir, even though Kefir has a lot and is a great source of probiotics. I personally, noticed some benefits from Kefir that I did not with oral probiotics. I just wanted to correct a previous incorrect comment FYI!

Depends ont he Kefir. Water kefir has very few probiotics. Coconut keifer has like 36 or so (I have onlly seen 1 specific probiotic with 37 strains and a couple of the same brand that have 32-34). the probiotic strains are not as tightly controlled in kefir, so they will tend to be different and possibly better for some people than a more controlled probiotic. I read that the human gut is supposed ot have a few hundred strains of probiotics, and the exact list can be different fro each person. There is even a place in the Boston area now doing "fecal transplants" to help people with very severe health challenges get those few hundred strains. Not sure what I would think of that... .
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snowwhite
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« Reply #6 on: March 06, 2019, 05:48:25 PM »

I have read a number of medical studies conducted over the last five years or so that are investigating the effects of the gut microbes (pre-biotics and probiotics) on mental health, which can in some cases be substantial. As it turns out, some of the precursor molecules that go on to create neurotransmitters in the brain come from the intestines and can be affected by what particular microbes grow in your intestine.

While the only research study I could find that is specific to borderline is just starting in Europe in 2019 and will not be completed until 2021, I wondered if anyone had heard anything from their doctors or had added these to their treatment.
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« Reply #7 on: March 13, 2019, 08:26:33 PM »

People with borderline personality disorder (BPD) are extremely moody and suffer from symptoms of depression and anxiety, problems regulating emotions and thoughts.

Results of two studies indicate that daily intake of omega-3 fish oil supplements which contain EPA and DHA, the beneficial omega-3 fatty acids found in seafood, are effective.

Excerpt
Can J Psychiatry. 2013 Jul;58(7):402-8.
Omega-3 fatty acid supplementation in adolescents with borderline personality disorder and ultra-high risk criteria for psychosis: a post hoc subgroup analysis of a double-blind, randomized controlled trial.
Amminger GP1, Chanen AM, Ohmann S, Klier CM, Mossaheb N, Bechdolf A, Nelson B, Thompson A, McGorry PD, Yung AR, Schäfer MR.
https://www.ncbi.nlm.nih.gov/pubmed/23870722


RESULTS: At baseline, erythrocyte n-3 PUFA levels correlated positively with psychosocial functioning and negatively with psychopathology. By the end of the intervention, n-3 PUFAs significantly improved functioning and reduced psychiatric symptoms, compared with placebo. Side effects did not differ between the treatment groups.

CONCLUSIONS: Long-chain n-3 PUFAs should be further explored as a viable treatment strategy with minimal associated risk in young people with BPD.
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LightAfterTunnel
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« Reply #8 on: March 14, 2019, 07:40:17 AM »

I Contain Multitudes: The Microbes Within Us and a Grander View of Life
Author: Ed Yong
Publisher: HarperCollins  (January 16, 2016)
Paperback: 368 pages
ISBN-10: '0062368605
ISBN-13: 978-0062368607




Hey snowwhite,

I recently read the book “I contain multitudes” by Ed Yong in which it recounts quite a lot of recent studies discussing gut microbes. And there is a section in which it talks specifically about the microbes and their effects on neurotransmitters as well as in regards to mental health. I don’t have the book with me but the book is quite well referenced with papers from within the last 5 years as well.

It’s truly a great read in itself and it might be worth checking out for general knowledge on the modern theories and limits of understanding of the mechanisms going on. However, I don’t remember any references directly related to BPD.

LAT
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hope2727
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« Reply #9 on: March 14, 2019, 08:24:41 AM »

Hi interesting topic. There is some peer reviewed empirical evidence that suggests probiotics may support various processes including distress tolerance HOWEVER ... these researchers are very clear that these are VERY specific strains of probiotics at very specific doses. The message they repeatedly emphasized is that there are so many specific strains and they are required in specific doses that are WAY larger over longer periods than people realize to be even moderately effective. Further research found that some subjects did repopulate their gut microbes, others the probiotic supplements delayed the repopulation and for some they had no effect. So this was also not what they expected as they have far to go to understand how the supplements helped some yet harmed others. Basically the bottom line is that there is not way to use them effectively without further research, most specific strains are not available to the public, and the supplements that are are not in the right combinations or doses. So yes interesting approach but not yet useful for the average person. If you want more info CBC radio had a couple of decent discussion available on line, and there are some decent scholarly articles published. 
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